Numerical Studies of Segmented Flows in Microchannels for Bio-Analytical Chip Applications
Segmented flows are a technique of increasing interest in lab-on-a-chip applications, such as bio-analytical assays for drug discovery or portable biological testing. These flows provide multiple advantages over continuous flows, but the knowledge base remains very limited. This project uses a research code to simulate an array of flow conditions for segmented droplets of the test fluid. The results are used to develop relations for quantities of interest, such as relative pressure drop and wall film thickness, as a function of relevant physical parameters. In addition, the three-dimensional velocity and pressure fields generated are used to physically explain certain poorly-understood aspects of these relations.